Orphan G Protein-Coupled Receptors and Novel Neuropeptides

Over the last decade it has been shown that orphan G protein-coupled receptors (GPCRs) can be used as targets to discover novel neuropeptides. A dozen neuropeptides have been identified through this approach. Each of these neuropeptides has opened new doors for our understanding of fundamental physi...

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Principais autores: Civelli, Olivier., Zhou, Qun-Yong., SpringerLink (Online service)
Formato: Digital
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Assuntos:
Ciências da vida.
Neurociências.
Toxicologia.
Endocrinologia.
Citologia.
Endereço do item:http://dx.doi.org/10.1007/978-3-540-78351-0
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spelling oai:localhost:123456789-2125622023-07-17T15:09:15Z Orphan G Protein-Coupled Receptors and Novel Neuropeptides Civelli, Olivier. Zhou, Qun-Yong. SpringerLink (Online service) Ciências da vida. Neurociências. Toxicologia. Endocrinologia. Citologia. Over the last decade it has been shown that orphan G protein-coupled receptors (GPCRs) can be used as targets to discover novel neuropeptides. A dozen neuropeptides have been identified through this approach. Each of these neuropeptides has opened new doors for our understanding of fundamental physiological or behavioral responses. For example the orexins, MCH and ghrelin carry fundamental roles in regulating food intake while neuropeptide S, neuromedin S, the prokineticins and the orexins are major players in modulating sleep and circadian rhythms. The chapters of this book review the latest research in the field, most of them are written by the original discoverers of the respective novel neuropeptide. Emphasis is set not only on their discovery but also on their functional significance. Since many of these neuropeptides are part of drug discovery programs, this book impacts academic as well as pharmaceutical research. 0 2022-10-11T17:42:22Z 2022-10-11T17:42:22Z 2008. Digital 57 O74 9783540783510 198632 http://dx.doi.org/10.1007/978-3-540-78351-0 http://dx.doi.org/10.1007/978-3-540-78351-0
institution Acervo SISBI
collection SIGAA
topic Ciências da vida.
Neurociências.
Toxicologia.
Endocrinologia.
Citologia.
spellingShingle Ciências da vida.
Neurociências.
Toxicologia.
Endocrinologia.
Citologia.
Civelli, Olivier.
Zhou, Qun-Yong.
SpringerLink (Online service)
Orphan G Protein-Coupled Receptors and Novel Neuropeptides
description Over the last decade it has been shown that orphan G protein-coupled receptors (GPCRs) can be used as targets to discover novel neuropeptides. A dozen neuropeptides have been identified through this approach. Each of these neuropeptides has opened new doors for our understanding of fundamental physiological or behavioral responses. For example the orexins, MCH and ghrelin carry fundamental roles in regulating food intake while neuropeptide S, neuromedin S, the prokineticins and the orexins are major players in modulating sleep and circadian rhythms. The chapters of this book review the latest research in the field, most of them are written by the original discoverers of the respective novel neuropeptide. Emphasis is set not only on their discovery but also on their functional significance. Since many of these neuropeptides are part of drug discovery programs, this book impacts academic as well as pharmaceutical research.
format Digital
author Civelli, Olivier.
Zhou, Qun-Yong.
SpringerLink (Online service)
author_facet Civelli, Olivier.
Zhou, Qun-Yong.
SpringerLink (Online service)
author_sort Civelli, Olivier.
title Orphan G Protein-Coupled Receptors and Novel Neuropeptides
title_short Orphan G Protein-Coupled Receptors and Novel Neuropeptides
title_full Orphan G Protein-Coupled Receptors and Novel Neuropeptides
title_fullStr Orphan G Protein-Coupled Receptors and Novel Neuropeptides
title_full_unstemmed Orphan G Protein-Coupled Receptors and Novel Neuropeptides
title_sort orphan g protein-coupled receptors and novel neuropeptides
publishDate 2022
url http://dx.doi.org/10.1007/978-3-540-78351-0
work_keys_str_mv AT civelliolivier orphangproteincoupledreceptorsandnovelneuropeptides
AT zhouqunyong orphangproteincoupledreceptorsandnovelneuropeptides
AT springerlinkonlineservice orphangproteincoupledreceptorsandnovelneuropeptides
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